This Cajun Chicken Pasta is full of flavor. Spicy Cajun chicken (by using my homemade Cajun seasoning!) with sweet bell peppers, mushrooms and tomatoes tossed with fettuccine in a wine cream sauce! SO delicious.

This spicy Cajun chicken pasta is my jam.

Cajun Chicken Pasta l SimplyScratch.com

I first posted this recipe back in 2012. That’s almost 5 years ago! Where has the time gone?

Recently I was digging around in the archives of this blog, looking for something “new” to make for dinner, when my eyes landed on this recipe. I remember making this all the time and then noticed how horrible the photos were and thought– Ummmm, no one would ever  want make this just by looking at these photos!

So I made this for dinner tonight and gave my old recipe an update. Not only by updating the photography (so you actually might want to make it) but also the recipe itself. The whole thing got simplified, so less dishes are dirtied and it’s more home-cook friendly.

Cajun Chicken Pasta l SimplyScratch.com

I love making this Cajun chicken pasta as much as I love to eat it. This slightly spicy and creamy pasta dish is absolutely my idea of comfort food.

Cajun Chicken Pasta l SimplyScratch.com

Start prepping all of your ingredients. If you work during the day, this can be done in advance. It will help speed things along and dinner will run smoother.

Cajun Chicken Pasta l SimplyScratch.com

Generously season 1-1/4 pounds of cubed chicken breasts with the 1-1/2 tablespoons of Cajun seasoning. I like making my own Cajun seasoning so I can control the spice.

Cajun Chicken Pasta l SimplyScratch.com

Heat up a few tablespoons of olive oil in your skillet over medium-high heat. When the pan is nice and hot; add in the seasoned chicken in an even layer and cook for 3 to 4 minutes before turning. Cook for about 8 to 10 minutes
total. Once cooked transfer the chicken to a clean plate.

Now that the chicken is cooked, it would be a good time to drop in 3/4 of a pound of fettuccine. Follow the package directions, most take 8 o 12 minutes so make sure you have enough time to make the sauce. My rule of thumb is that the sauce can always wait for the pasta, the pasta should never wait for the sauce.

Cajun Chicken Pasta l SimplyScratch.com

Add a little more olive oil if needed to the skillet and toss in the thinly sliced onions, peppers and the quartered mushrooms.

Cajun Chicken Pasta l SimplyScratch.com

Once the vegetables start to soften but are still a little firm, add in the minced garlic and cook 1 minute.

Cajun Chicken Pasta l SimplyScratch.com

Next, pour in the wine and use a wooden spoon to scrape up any delicious browned bits on the bottom of the pan and reduce for a minute or two.

Cajun Chicken Pasta l SimplyScratch.com

Next, reduce the heat to medium-low and add in the diced tomatoes, whole milk and heavy cream.

Cajun Chicken Pasta l SimplyScratch.com

Stir to combine and season with 1/2 teaspoon of kosher salt and 1/4 teaspoon of black pepper. Then bring the sauce up to a bubble and cook, stirring often until thick.

Cajun Chicken Pasta l SimplyScratch.com

Once the pasta is cooked, drain and add it along with the cooked Cajun chicken to the vegetable cream sauce.

Cajun Chicken Pasta l SimplyScratch.com

Give it all a toss, taste and season with more salt and pepper if needed. Lastly, sprinkle with a little chopped parsley before serving.

Cajun Chicken Pasta l SimplyScratch.com

The flavors in this pasta dish are wonderful! It has some heat, but it’s a delicious addictive heat and the luscious creamy sauce is just lovely. And it’s so close to being classified as a one-pan meal, making this recipe simple for any night of the week.

I serve it with a fresh garden salad and maybe a glass of white wine to wash it all down.

Enjoy!

Cajun Chicken Pasta l SimplyScratch.com

My cookbook Simply Scratch : 120 Wholesome Homemade Recipes Made Easy is now available! CLICK HERE for details and THANK YOU in advance!

Skillet Cajun Chicken Pasta
Yield: serves 4 to 6

Skillet Cajun Chicken Pasta

This skillet Cajun chicken pasta is full of flavor! Cajun seasoned chicken, bell peppers, mushrooms and tomatoes tossed with fettuccine in a cream sauce!

Prep Time 20 minutes
Cook Time 25 minutes
Total Time 45 minutes

Ingredients

  • 1-1/4 pounds boneless skinless chicken breasts
  • 1-1/2 tablespoons of homemade Cajun seasoning
  • 1 to 2 tablespoons olive oil, as needed
  • 1 small yellow onion, sliced vertically into thin strips
  • 1 (8 ounce) container of mushrooms, halved or quartered if large
  • 1/2 a yellow bell pepper, sliced (about 1/2 cup)
  • 1/2 an orange bell pepper, sliced (about 1/2 cup)
  • 3 garlic cloves, minced
  • 1/3 cup dry white wine (I use Sauvignon Blanc) or chicken broth may be substituted
  • 2 medium Roma tomatoes, seeded and diced
  • 3/4 cup heavy cream
  • 3/4 cup whole milk
  • 3/4 pound fettuccine noodles
  • kosher salt and black pepper, to taste
  • fresh parsley, roughly chopped for garnish

Instructions

Bring a large pot of water to boil.

Season the chicken pieces with 1-1/2 tablespoons of the Cajun seasoning.

Heat a large 12-inch skillet with a few tablespoons of olive oil over medium-high heat. Once hot, place the seasoned chicken in an even layer in the pan. Cook for 4-5 minutes before turning. Repeat for another 4-5 minutes or until the chicken is fully cooked. Remove the chicken to a clean plate.

Drop the pasta into the waiting boiling water and add in a tablespoon of sea salt. Follow package directions to cook the pasta al dente.

Add a teaspoon more of olive oil to the pan if needed and add in the onions, mushrooms and bell pepper. Cook for 5-6 minutes or until they are soft yet still a bit firm.

Add in the in the garlic and cook for 1 minute before pouring in the wine. Use a wooden spoon to scrape up the browned bits on the bottom of the pan and cook for 1 minute.

Next add in the tomatoes, heavy cream and whole milk. Stir, bringing this to a bubble until it has thickened a bit. Drain and add in the cooked pasta and also the Cajun chicken. Toss together and taste, seasoning with more salt and pepper as needed.

Serve with a little chopped parsley on top and enjoy!

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Cajun Chicken Pasta l SimplyScratch.com